Dmt-Dcytidine (N6-Benzoyl) Cyanoethyl Phosphoramidite) - Names and Identifiers
Dmt-Dcytidine (N6-Benzoyl) Cyanoethyl Phosphoramidite) - Physico-chemical Properties
Molecular Formula | C43H54N5O8P
|
Molar Mass | 799.89 |
pKa | 10.01±0.20(Predicted) |
Storage Condition | 2-8°C |
Dmt-Dcytidine (N6-Benzoyl) Cyanoethyl Phosphoramidite) - Introduction
ibu-dC is a phosphoramidite monomer, fully known as 2-isobutyryl-1-(β-D-deoxyribosyl)-cyproside. It is an organic compound with the following properties:
1. physical properties: ibu-dC is a white crystalline solid, sometimes yellow. Its melting point is between about 165-176 degrees Celsius.
2. Chemical properties: ibu-dC is insoluble in water and soluble in some organic solvents, such as dimethyl sulfoxide and acetonitrile. It is an esterification reagent that reacts with hydroxide to form an ester.
3. use: ibu-dC is mainly used for research and synthesis of nucleic acid molecules, especially in the process of DNA synthesis. It can be used as a raw material for nucleic acid fluorescent probes, for the synthesis of fluorescent probes and labeling reagents, and for nucleic acid sequence analysis, gene sequencing and diagnostics.
4. preparation method: the preparation method of ibu-dC is mainly realized by chemical synthesis. A common synthesis method is to modify the existing nucleotide molecules, and then introduce isobutyryl and deoxyribosyl in the substrate through chemical reaction, and finally obtain ibu-dC.
5. Safety Information: There is limited information on the safety and toxicity of the ibu-dC. As a chemical reagent, the use should comply with the laboratory safety procedures. Direct contact with ibu-dC may be irritating and sensitizing to the skin, eyes and mucous membranes, so personal protective measures should be taken to avoid inhalation, ingestion or swallowing. Personal protective equipment such as safety gloves, goggles and protective clothing should be used. Seek medical assistance in case of accidental exposure or discomfort.
Last Update:2024-04-09 19:05:44